【临床试验招募】肾癌培唑帕尼辅助治疗对术后肾细胞癌的有效性和安全性研究
发布:2019-03-22 11:00:57
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题目和背景信息

适应症: 肾细胞癌辅助治疗
 试验通俗题目: 培唑帕尼辅助治疗对术后肾细胞癌的有效性和安全性研究
 试验专业题目: 随机、双盲、安慰剂对照、III期研究评价培唑帕尼辅助治疗肾切除术后的局限期肾癌患者的有效性和安全性
 试验方案编号: VEG113387
 临床申请受理号: 企业选择不公示
 药物名称: 培唑帕尼
 药物类型: 化学药物

 临床试验信息

 1、试验目的
评价培唑帕尼作为辅助治疗对肾切除术后局限性或局部进展性肾细胞癌患者的有效性和安全性。
 2、试验设计(单选)
  试验分类: 安全性和有效性
  试验分期: III期
  设计类型: 平行分组
  随机化: 随机化
  盲法: 双盲
  试验范围: 国际多中心试验
 3、受试者信息
年龄   18岁(最小年龄)至 无岁(最大年龄)
性别   男+女
健康受试者   无
入选标准
1 诊断为肾细胞癌,组织学为透明细胞或以透明细胞为主型。
2 符合基线期无病状态的标准。
3 器官系统功能良好
4 非转移性疾病(M0)受试者,符合综合2010年版AJCC 病理TNM分期标准和Fuhrman核分级之一:1)pT2,G3或G4,N0;或者 2)pT3,Gany,N0;或者 3)pT4,Gany,N0:或者 4)pTany,Gany,N1
5 过去未接受过针对RCC的辅助治疗或新辅助治疗。
排除标准
1 局部复发RCC、双侧RCC或其它恶性肿瘤病史
2 慢性活动性肝炎的病史,包括乙肝病毒(HBV)或丙肝病毒(HCV)携带者
3 人类免疫缺陷病毒(HIV)感染病史
4 具有临床意义的、可能会增加胃肠道出血风险的胃肠道异常
目标入组人数   国际多中心试验:总体1500人, 中国40人;
实际入组人数   登记人暂未填写该信息
 4、试验分组
试验药
序号 名称 用法
1 培唑帕尼 片剂;规格200mg;口服,每天一次,起始剂量每次 600mg, 用药时程,连续用药,共计8到12周;然后根据受试者的安全性和耐受性,由研究者根据方案规定决定是否增加到800mg剂量水平或者保持600mg剂量水平。治疗总时程为12个月。
对照药
序号 名称 用法
1 安慰剂 片剂;规格200mg;口服,每天一次,起始剂量每次 600mg, 用药时程,连续用药,共计8到12周;然后根据受试者的安全性和耐受性,由研究者根据方案规定决定是否增加到800mg剂量水平或者保持600mg剂量水平。治疗总时程为12个月。
 5、终点指标
主要终点指标及评价时间
序号 指标 评价时间 终点指标选择
1 无病生存期(DFS) 当获得578个DFS事件时进行评价。 有效性指标
次要终点指标及评价时间
序号 指标 评价时间 终点指标选择
1 总生存期(OS) 当获得578个DFS事件时进行评价。 有效性指标
2 生活质量 当获得578个DFS事件时进行评价。 有效性指标+安全性指标
3 安全性和耐受性 当获得578个DFS事件时进行评价。 安全性指标
4 年DFS率(如1年、2年等) 当获得578个DFS事件时进行评价。 有效性指标
 6、数据安全监察委员会(DMC):    有
 7、为受试者购买试验伤害保险:   有

研究者信息

各参加机构信息
序号 机构名称 国家 省(州) 城市
1 Memorial Sloan-Kettering Cancer Ctr-New York-United States-C United States New York New York
2 北京大学第一医院 中国 北京 北京
3 中国医学科学院肿瘤医院 中国 北京 北京
4 上海交通大学医学院附属仁济医院 中国 上海 上海
5 天津肿瘤医院 中国 天津 天津
6 北京大学第三医院 中国 北京 北京
7 浙江大学医学院附属第一医院 中国 浙江 杭州
8 复旦大学附属华山医院 中国 上海 上海
9 浙江大学医学院附属第二医院 中国 浙江 杭州
10 上海瑞金医院 中国 上海 上海
11 华中科技大学同济医学院附属同济医院 中国 湖北 武汉
12 复旦大学附属肿瘤医院 中国 上海 上海
13 COIBA Centro de oncología e investig-Berazategui Argentina Buenos Aires Berazategui
14 Instituto Alexander Fleming-Capital Federal Argentina Buenos Aires Capital Federal
15 Hospital Alemán-Ciudad de Buenos Aires Argentina Buenos Aires Ciudad de Buenos Aires
16 Instituto de Investigaciones Clinicas Cipolletti-Cipolletti Argentina Río Negro Cipolletti
17 CER Instituto Medico-Quilmes Argentina Quilmes Quilmes
18 Instituto Oncologico de Cordoba-Cordoba Argentina Córdova Córdoba
19 Instituto Médico Especializado-Ciudad de Buenos Aires Argentina Buenos Aires Ciudad de Buenos Aires
20 Centro Oncologico de Rosario-Rosario Argentina Santa Fe Rosario
21 CEMIC-Ciudad Autonoma de Bueno Argentina Buenos Aires Ciudad Autonoma de Bueno
22 Hospital Britanico de Buenos Aires-Ciudad Autónoma de Bueno Argentina Buenos Aires Ciudad Autonoma de Buenos Aires
23 Fundacion RUSCULLEDA-Córdoba Argentina Córdova Córdoba
24 ISIS Clinica Especializada-Santa Fe Argentina Santa Fe Santa Fe
25 Sanatorio de la Providencia-Ciudad Autonoma de Bueno Argentina Buenos Aires Ciudad Autónoma de Buenos Aires
26 Investigaciones Clinicas Ciudad Autonoma de Buenos-Buenos Aires Argentina Buenos Aires Ciudad Autónoma de Buenos Aires
27 Centro Medico San Roque-San Miguel de Tucuman Argentina San Miguel de Tucumán San Miguel de Tucumán
28 Universitaetsklinik Innsbruck-Innsbruck Austria Innsbruck Innsbruck
29 LKH Salzburg-Salzburg Austria Salzburg Salzburg
30 LKH Salzburg-Salzburg Austria Salzburg Salzburg
31 AKH Wien-Vienna Austria Vienna Vienna
32 LKH Graz-Graz Austria Graz Graz
33 KH Hietzing mit Neurolog. Zentrum Rosenhügel-Vienna Austria Vienna Vienna
34 Centre Hospitalier Universitaire de Liège-Liege Belgium Liège Liège
35 Clinique St Elisabeth-Namur Belgium Namur Namur
36 AZ St Augustinus-Wilrijk Belgium Wilrijk Wilrijk
37 UZ Brussel-Brussel Belgium Jette Jette
38 Heilig Hart Ziekenhuis 3-Roeselare Belgium Roeselare Roeselare
39 JESSA Ziekenhuis Campus Virga Jesse-Hasselt Belgium Hasselt Hasselt
40 Hospital Erasto Gaertner-Curitiba Brazil Paraná Curitiba
41 Hospital Israelita Albert Einstein-Sao Paulo Brazil Sao Paulo Sao Paulo
42 Hospital das Clínicas da Universidade Federal-Belo Horizonte Brazil Minas Gerais Belo Horizonte
43 Instituto Nacional do Cancer - INCA-Rio de Janeiro Brazil Rio De Janeiro Rio de Janeiro
44 Hospital Sirio Libanes-Sao Paulo Brazil Sao Paulo Sao Paulo
45 Universidade Estadual de Campinas (UNICAMP)-Campinas Brazil Sao Paulo Campinas
46 Hospital Universitário Pedro Ernesto-UERJ-Rio de Janeiro Brazil Rio De Janeiro Rio De Janeiro
47 Instituto do Cancer do Estado de Sao Paulo-Sao Paulo Brazil Sao Paulo Sao Paulo
48 Fundacao PIO XII - Hospital de Cancer de Barretos-Barretos Brazil Sao Paulo Barretos
49 Clinica de Oncologia Medica-Sao Paulo Brazil Sao Paulo Sao Paulo
50 Hospital de Caridade de Ijui-Ijui Brazil Rio Grande Do Sul Ijui
51 Hospital santa marcelina-Sao Paulo Brazil Sao Paulo Sao Paulo
52 PUC-RS/Hospital Sao Lucas-Porto Alegre Brazil Rio Grande Do Sul Porto Alegre
53 Cross Cancer Institute-Edmonton Canada Alberta Edmonton
54 Tom Baker Cancer Centre-Calgary Canada Alberta Calgary
55 London Health Sciences Centre- Lawson Health-London Canada Ontario London
56 Ottawa Regional Cancer Centre-Ottawa Canada Ontario Ottawa
57 Lakeridge Health-Oshawa Canada Ontario Oshawa
58 Princess Margaret Hospital-Toronto Canada Ontario Toronto
59 CHUQ-Hotel Dieu de Quebec-Quebec Canada Québec Québec
60 The Moncton Hospital-Moncton Canada New Brunswick Moncton
61 Queen Elizabeth II Health Sciences Centre 2-Halifax Canada Nova Scotia Halifax
62 Juravinski Cancer Centre-Hamilton Canada Ontario Hamilton
63 CHUM Hopital Notre Dame-Quebec Canada Québec Montreal
64 Vancouver Prostate Centre-Vancouver Canada British Columbia Vancouver
65 Sunnybrook Health Sciences Centre-Toronto Canada Ontario Toronto
66 Fundación Arturo López Pérez-Santiago-Chile-C Chile Región Metro De Santiago Santiago
67 Instituto Oncologico-Vina del Mar-Chile-C Chile Valparaíso Vina del Mar
68 Masarykova nemocnice-Usti nad Labem-Czech Republic-C Czech Republic Usti nad Labem Usti nad Labem
69 VFN Praha 2-Praha 2-Czech Republic-C Czech Republic Praha 2 Praha 2
70 Nemocnice Na Bulovce-Praha 8-Czech Republic-C Czech Republic Praha 8 Praha 8
71 FNsP u sv. Anny-Brno-Czech Republic-C Czech Republic Brno Brno
72 FN Plzen 2-Plzen-Czech Republic-C Czech Republic Plzen Plzen
73 FN Hradec Kralove 5-Hradec Kralove-Czech Republic-C Czech Republic Hradec Kralove Hradec Kralove
74 FN Olomouc-Olomouc-Czech Republic-C Czech Republic Olomouc Olomouc
75 FNsP Ostrava- Poruba-Ostrava - Poruba-Czech Republic-C Czech Republic Ostrava - Poruba Ostrava - Poruba
76 Masarykuv onkologicky ustav-Brno-Czech Republic-C Czech Republic Brno Brno
77 Nemocnice Novy Jicin-Novy Jicin-Czech Republic-C Czech Republic Novy Jicin Novy Jicin
78 Herlev Hospital-Herlev-Denmark-C Denmark Herlev Herlev
79 Aarhus Universitetshospital, Aarhus Sygehus-Aarhus-Denmark-C Denmark Aarhus Aarhus
80 Odense Universitetshospital-Odense C-Denmark-C Denmark Odense C Odense C
81 Centre Francois Baclesse-Caen cedex 5-France-C France Caen Cedex 05 Caen Cedex 05
82 Institut Mutualiste Montsouris-Paris-France-C France Paris Paris
83 Centre Eugène Marquis-Rennes-France-C France Rennes Rennes
84 CHU de Poitiers - Hopital de la Milétrie-Poitiers cedex-France-C France Poitiers Cedex Poitiers Cedex
85 HUS - Nouvel Hopital Civil-Strasbourg cedex-France-C France Strasbourg Cedex Strasbourg Cedex
86 Institut de Cancérologie Paul Papin-Angers cedex 9-France-C France Angers cedex 9 Angers cedex 9
87 Institut Cancérologie de l’Ouest - René Gauducheau-Saint-Herblain cedex-France-C France Saint Herblain Saint Herblain
88 Hopital Européen Georges Pompidou-Paris cedex 15-France-C France Paris Cedex 15 Paris Cedex 15
89 Polyclinique Courlancy-Reims-France-C France Reims Reims
90 CHRU de Tours - Hopital Bretonneau-Tours cedex 9-France-C France Tours Cedex 9 Tours Cedex 9
91 Clinique Sainte Marguerite-Hyeres-France-C France Hyeres Hyeres
92 CHU de Montpellier - Hopital Saint-Eloi-Montpellier cedex 5-France-C France Montpellier Cedex 5 Montpellier Cedex 5
93 CHU de Bordeaux - Hopital Saint André-Bordeaux-France-C France Bordeaux Bordeaux
94 Centre Léon Bérard-Lyon cedex 08-France-C France Lyon Cedex 08 Lyon Cedex 08
95 CHU de Marseille - Hopital de la Timone-Marseille cedex 5-France-C France Marseille cedex 5 Marseille cedex 5
96 CHU de Besancon - Hopital Jean Minjoz-Besancon cedex-France-C France Besancon cedex Besancon cedex
97 Centre Jean Bernard - Clinique Victor Hugo-Le Mans-France-C France Le Mans Le Mans
98 Clinique Pasteur-Toulouse-France-C France Toulouse Toulouse
99 Clinique Sainte Anne-Strasbourg cedex-France-C France Strasbourg cedex Strasbourg cedex
100 Gem. Praxis Drs. Woerner und Rudolph-Kirchheim-Germany-C Germany Baden-Wuerttemberg Kirchheim
101 Universitaetsklinikum Marburg-Urologie-Marburg-Germany-C Germany Hessen Marburg
102 Praxis Dr. med. Jochen Wilke-Fuerth-Germany-C Germany Bayern Fuerth
103 Helios Klinikum Erfurt-Urologie-Erfurt-Germany-C Germany Freistaat Thüringen Erfurt
104 Universitaetsklinikum Bonn-Urologie-Bonn-Germany-C Germany Nordrhein-Westfalen Bonn
105 Klinikum Offenbach GmbH-Urologische Klinik-Offenbach-Germany-C Germany Hessen Offenbach
106 Universitaetsklinikum Muenster-Urologie-Muenster-Germany-C Germany Nordrhein-Westfalen Muenster
107 Uniklinik Schleswig-Holstein-Campus Luebeck-Urolog-Luebeck-Germany-C Germany Schleswig-Holstein Luebeck
108 Universitaetsklinikum des Saarlandes-Urologie-Homburg/Saar-Germany-C Germany Saarland Homburg
109 Universitaetsklinikum Ulm-Urologie-Ulm-Germany-C Germany Baden-Wuerttemberg Ulm
110 Praxis Dr. med. Ralf Eckert-Eisleben-Germany-C Germany Sachsen-Anhalt Eisleben
111 Charite-Campus Mitte-Urologie-Berlin-Germany-C Germany Berlin Berlin
112 Universitaetsklinikum Aachen-Urologie-Aachen-Germany-C Germany Nordrhein-Westfalen Aachen
113 Praxis Dr. med. Goetz Geiges-Berlin-Germany-C Germany Berlin Berlin
114 Katharinenhospital Stuttgart-Stuttgart-Germany-C Germany Baden-Wuerttemberg Stuttgart
115 Universitaetsklinikum Jena-Urologie-Jena-Germany-C Germany Thueringen Jena
116 Krankenhaus Am Urban-Berlin-Germany-C Germany Berlin Berlin
117 Waldkrankenhaus St. Marien-Erlangen-Germany-C Germany Bayern Erlangen
118 Praxis Dr. med. Toralf Kellner-Plauen-Germany-C Germany Sachsen Plauen
119 Klinikum rechts der Isar-Urologie-Muenchen-Germany-C Germany Bayern Muenchen
120 Klinikum der J. W. Goethe-Universitaet-Med. K. II-Frankfurt-Germany-C Germany Hessen Frankfurt
121 Kreiskrankenhaus Sigmaringen-Urologie-Sigmaringen-Germany-C Germany Baden-Wuerttemberg Sigmaringen
122 Praxis Dr. med. Hans Werner Tessen-Goslar-Germany-C Germany Niedersachsen Goslar
123 Universitaetsklinikum der GHS Essen-Tumorforschung-Essen-Germany-C Germany Nordrhein-Westfalen Essen
124 Martin-Luther-Universitaet Halle-Urologie-Halle-Germany-C Germany Sachsen-Anhalt Halle
125 Johannes-Gutenberg-Universitaet Mainz-Urologie-Mainz-Germany-C Germany Rheinland-Pfalz Mainz
126 Studienzentrum Onkologie Ravensburg im Brustzentru-Ravensburg-Germany-C Germany Baden-Wuerttemberg Ravensburg
127 Staedtische Kliniken Neuss Lukaskrankenhaus-Urol.-Neuss-Germany-C Germany Nordrhein-Westfalen Neuss
128 Caritas-Krankenhaus St. Josef-Urologie-Regensburg-Germany-C Germany Bayern Regensburg
129 Duisburger Fachaerztegemeinschaft Urologie-Duisburg-Germany-C Germany Nordrhein-Westfalen Duisburg
130 Klinikum Nordoberpfalz-Weiden-Urologie-Weiden-Germany-C Germany Bayern Weiden
131 Zeisigwaldkliniken Bethanien-Urologie-Chemnitz-Germany-C Germany Sachsen Chemnitz
132 Universitaetsklinikum Eppendorf-Urologie-Hamburg-Germany-C Germany Hamburg Hamburg
133 Medizinische Hochschule Hannover-Urologie-Hannover-Germany-C Germany Niedersachsen Hannover
134 Diakonissenkrankenhaus Dessau gGmbH-Urologie-Dessau-Germany-C Germany Sachsen-Anhalt Dessau
135 Klinikum Bremen-Mitte gGmbH-Urologische Klinik-Bremen-Germany-C Germany Bremen Bremen
136 Universitaetsklinikum Tuebingen-Urologie-Tuebingen-Germany-C Germany Baden-Wuerttemberg Tuebingen
137 Klinikum Braunschweig-Urologische Klinik-Braunschweig-Germany-C Germany Niedersachsen Braunschweig
138 Kliniken Maria Hilf-Klinik fuer Urologie-Moenchengladbach-Germany-C Germany Nordrhein-Westfalen Moenchengladbach
139 Marien-Krankenhaus-Bergisch Gladbach-Germany-C Germany Nordrhein-Westfalen Bergisch Gladbach
140 Gem. Praxis Drs. Nusch und Kalhori-Velbert-Germany-C Germany Nordrhein-Westfalen Velbert
141 Klinikum Grosshadern-Urologie-Muenchen-Germany-C Germany Bayern Muenchen
142 VITURO, Ges.f. klinische Studien, Ur-Leipzig-Germany-C Germany Sachsen Leipzig
143 University Hospital of Patras-Patra-Greece-C Greece Rio-Patras Rio-Patras
144 University Hospital of Heraklion-Heraklion, Crete-Greece-C Greece Heraklion, Crete Heraklion, Crete
145 General Hospital of Athens Greece Athens Athens
146 Agios Savvas Hospital-Athens-Greece-C Greece Athens Athens
147 Euromedica General Clinic of Thessaloniki-Thessaloniki-Greece-C Greece Thessaloniki Thessaloniki
148 Vas Megyei Markusovszky Lajos Kórház-Szombathely-Hungary-C Hungary Szombathely Szombathely
149 Országos Onkológiai Intézet-Budapest-Hungary-C Hungary Budapest Budapest
150 B-A-Z Megyei Kórház-Miskolc-Hungary-C Hungary Miskolc Miskolc
151 Szabolcs-Szatmár-Bereg Megyei Onkormányzat-Nyíregyháza-Hungary-C Hungary Nyíregyháza Nyíregyháza
152 Semmelweis Egyetem-Budapest-Hungary-C Hungary Budapest Budapest
153 Fov Onk. Egyesített St István-St László Kórház-RI-Budapest-Hungary-C Hungary Budapest Budapest
154 Beaumont Hospital-Dublin 9-Ireland-C Ireland Dublin Dublin
155 Mater Misericordiae Hospital-Dublin-Ireland-C Ireland Dublin Dublin
156 University Hospital Galway-Galway-Ireland-C Ireland Galway Galway
157 Cork University Hospital-Cork-Ireland-C Ireland Wilton Cork
158 Adelaide & Meath Hospital-Dublin-Ireland-C Ireland Dublin Dublin
159 St Vincent's University Hospital - D-Dublin-Ireland-C Ireland Dublin Dublin
160 Mater Private Hospital-Dublin-Ireland-C Ireland Dublin Dublin
161 Rabin MC, Campus Beilinson-Petach Tikva-Israel-C Israel Petah-Tikva Petah-Tikva
162 Kaplan MC-Rehovot-Israel-C Israel Rehovot Rehovot
163 Rambam MC-Haifa-Israel-C Israel Haifa Haifa
164 Hadassah Ein-Kerem MC.-Jerusalem-Israel-C Israel Jerusalem Jerusalem
165 Assaf Harofeh MC-Zrifin-Israel-C Israel Zrifin Zrifin
166 Tel-Aviv Sourasky MC-Tel Aviv-Israel-C Israel Tel Aviv Tel Aviv
167 Policlinico di Modena - A.O. Universitaria-Modena-Italy-C Italy Emilia-Romagna Modena
168 Fondazione IRCCS Policlinico San Matteo-Pavia-Italy-C Italy Lombardia Pavia
169 Ospedale San Donato - USL 8-Arezzo-Italy-C Italy Toscana Arezzo
170 Istituto Nazionale Tumori-Milano-Italy-C Italy Lombardia Milano
171 Azienda Ospedaliera Santa Maria-Terni-Italy-C Italy Umbria Terni
172 Ist per la Ricerca ed il Trattamento del Cancro-Candiolo (TO)-Italy-C Italy Piemonte Candiolo
173 AO Rilievo Nazionale A.Cardarelli-Napoli-Italy-C Italy Campania Napoli
174 AOU di Bologna Policlinico S.Orsola - Malpighi-Bologna-Italy-C Italy Emilia-Romagna Bologna
175 Azienda Ospedaliera San Camillo Forlanini-Roma-Italy-C Italy Lazio Roma
176 Ist. Scientifico Romagnolo Studio e Cura Tumori-Meldola (FC)-Italy-C Italy Emilia-Romagna Meldola (FC)
177 Azienda Ospedaliera Sacro Cuore - Don Calabria-Negrar (Verona)-Italy-C Italy Veneto Negrar
178 I.F.O. Regina Elena - San Gallicano-Roma-Italy-C Italy Lazio Roma
179 Yamagata University Hospital-Yamagata-Japan-C Japan Yamagata Yamagata
180 Keio University Hospital-Tokyo-Japan-C Japan Tokyo Tokyo
181 Yokohama City University Hospital-Kanagawa-Japan-C Japan Kanagawa Kanagawa
182 Okayama University Hospital-Okayama-Japan-C Japan Okayama Okayama
183 The Cancer Institute Hospital of JFCR (Ariake)-Tokyo-Japan-C Japan Tokyo Tokyo
184 Hokkaido University Hospital-Hokkaido-Japan-C Japan Hokkaido Hokkaido
185 Nippon Medical School Hospital-Tokyo-Japan-C Japan Tokyo Tokyo
186 Kyushu University Hospital-Fukuoka-Japan-C Japan Fukuoka Fukuoka
187 Kinki University Hospital-Osaka-Japan-C Japan Osaka Osaka
188 Hamamatsu University School of Medicine-Shizuoka-Japan-C Japan Shizuoka Shizuoka
189 Tokyo Women's Medical University Hospital-Tokyo-Japan-C Japan Tokyo Tokyo
190 Sapporo Medical University Hospital-Hokkaido-Japan-C Japan Hokkaido Hokkaido
191 National Cancer Center-Gyeonggi-do-Korea-C Korea, Republic of Gyeonggi-do Gyeonggi-do
192 Seoul National University Bundang Hospital-Seongnam-si, Gyeonggi-do-Korea-C Korea, Republic of Seongnam-si Gyeonggi-do Seongnam-si Gyeonggi-do
193 Korea University Anam Hospital-Seoul-Korea-C Korea, Republic of Seoul Seoul
194 Samsung Medical Center-Seoul-Korea-C Korea, Republic of Seoul Seoul
195 Severance Hospital, YUCM-Seoul-Korea-C Korea, Republic of Seodaemun-gu, Seoul Seodaemun-gu, Seoul
196 Seoul National University Hospital 1-Seoul-Korea-C Korea, Republic of Seoul Seoul
197 Chonbuk National University Hospital-Chonju/Jeonju-Korea-C Korea, Republic of Jeonju Jeonju
198 Chungnam National University Hospital-Daejeon-Korea-C Korea, Republic of Daejeon Daejeon
199 Asan Medical Center-Seoul-Korea-C Korea, Republic of Seoul Seoul
200 Centre Hospitalier de Luxembourg-Luxembourg-Luxembourg-C Luxembourg Luxembourg Luxembourg
201 Wojewodzki Szpital Specjalistyczny-Wroclaw-Poland-C Poland Wroclaw Wroclaw
202 NZOZ VESALIUS-Krakow-Poland-C Poland Kraków Kraków
203 Centrum Onkologii Instytut im.M.Sklodowskiej-Curie-Krakow-Poland-C Poland Krakow Krakow
204 Przychodnia Lekarska NZOZ Komed-Konin-Poland-C Poland Konin Konin
205 Centrum Medyczne Ostrobramska NZOZ MAGODENT-Warszawa-Poland-C Poland Warszawa Warszawa
206 Centrum Onkologii Ziemi Lubelskiej-Lublin-Poland-C Poland Lublin Lublin
207 Szpital Kliniczny Przemienienia Panskiego-Poznan-Poland-C Poland Poznan Poznan
208 NZOZ Mazowiecki Szpital Onkologiczny-Wieliszew-Poland-C Poland Wieliszew Wieliszew
209 Centrum Onkologii-Instytut im.M.Sklodowskiej-Curie-Warszawa-Poland-C Poland Warszawa Warszawa
210 Wojewodzkie Centrum Onkologii-Gdansk-Poland-C Poland Gdansk Gdansk
211 ONKOLMED Lecznica Onkologiczna-Warszawa-Poland-C Poland Warszawa Warszawa
212 Akademicki Szpital Kliniczny im. Jana Mikulicza-Wroclaw-Poland-C Poland Wroclaw Wroclaw
213 Wojewodzki Szpital Specjalistyczny im.M. Kopernika-Lodz-Poland-C Poland Lodz Lodz
214 Russian Scientific Center of Roentgeno-Radiology-Moscow-Russian Federation-C Russian Federation Moscow Moscow
215 Russian Cancer Research Centre n.a Blokhin,RAMS-Moscow-Russian Federation-C Russian Federation Moscow Moscow
216 City Hospital #2-Saint Petersburg-Russian Federation-C Russian Federation Saint Petersburg Saint Petersburg
217 Petrov Research Institute of Oncology-St. Petersburg-Russian Federation-C Russian Federation St. Petersburg St. Petersburg
218 Regional Clinical Oncology Dispensary-Ryazan-Russian Federation-C Russian Federation Ryazan Ryazan
219 Tatarstan Republic Clinical Oncology Dispensary-Kazan-Russian Federation-C Russian Federation Kazan Kazan
220 Sverdlovsk Regional Clinical Hospital-Ekaterinburg-Russian Federation-C Russian Federation Ekaterinburg Ekaterinburg
221 Rostov Central Clinical Hospital-Rostov on Don-Russian Federation-C Russian Federation Rostov-na-Donu Rostov-na-Donu
222 GUZ Russian Federation Ufa Ufa
223 Stavropol Regional Clinical Oncological Dispensary-Stavropol-Russian Federation-C Russian Federation Stavropol Stavropol
224 Regional Oncology Dispensary-Chelyabinsk-Russian Federation-C Russian Federation Chelyabinsk Chelyabinsk
225 Oncology Dispensary-Omsk-Russian Federation-C Russian Federation Omsk Omsk
226 Arkhangelsk Regional Oncology Dispensery-Arkhangelsk-Russian Federation-C Russian Federation Arkhangelsk Arkhangelsk
227 Medical Roentgenology Resesarch Center-Obninsk-Russian Federation-C Russian Federation Obninsk Obninsk
228 Altai Regional Oncology Dispensary-Barnaul-Russian Federation-C Russian Federation Barnaul Barnaul
229 Univerzitna nemocnica L.Pasteura Kosice-Kosice-Slovakia-C Slovakia Kosice Kosice
230 FNsP F.D. Roosevelta-Banska Bystrica-Slovakia-C Slovakia Banska Bystrica Banska Bystrica
231 Fakultna nemocnica s poliklinikou Zilina-Zilina-Slovakia-C Slovakia Zilina Zilina
232 Univerzitna nemocnica Martin-Martin-Slovakia-C Slovakia Martin Martin
233 Univerzitna nemocnica Bratislava-Bratislava-Slovakia-C Slovakia Bratislava Bratislava
234 Instituto Valenciano Oncologico-Valencia-Spain-C Spain Valencia Valencia
235 Hospital 12 De Octubre-Madrid-Spain-C Spain Madrid Madrid
236 Hospital Reina Sofia 1-Cordoba-Spain-C Spain Córdova Córdoba
237 Hospital Virgen del Rocío-Sevilla-Spain-C Spain Sevilla Sevilla
238 Hospital Central de Asturias-Oviedo-Spain-C Spain Oviedo Oviedo
239 Hospital Clinico Universitario Virgen Victoria 2-Malaga-Spain-C Spain Málaga Málaga
240 Hospital Universitario Valle de Hebr-Barcelona-Spain-C Spain Barcelona Barcelona
241 Hospital Gregorio Maranon-Madrid-Spain-C Spain Madrid Madrid
242 Hospital Germans Trias I Pujol 2-Badalona-Spain-C Spain Badalona Badalona
243 Centro Oncológico Integral Clara Campal-Madrid-Spain-C Spain Madrid Madrid
244 Hospital Clinic-Barcelona-Spain-C Spain Barcelona Barcelona
245 Complejo Hospitalario Nuestra Sra. de Valme-Sevilla-Spain-C Spain Sevilla Sevilla
246 MD Anderson-Madrid-Spain-C Spain Madrid Madrid
247 Ege University SoM-Bornova/Izmir-Turkey-C Turkey Izmir Izmir
248 Cukurova University School of Medicine-Adana-Turkey-C Turkey Adana Adana
249 Ankara University Medical Faculty Ce-Ankara-Turkey-C Turkey Ankara Ankara
250 Hacettepe University School of Medicine-Ankara-Turkey-C Turkey Ankara Ankara
251 Istanbul University Oncology Institute-Istanbul-Turkey-C Turkey Istanbul Istanbul
252 Royal Free Hospital-London-United Kingdom-C United Kingdom London London
253 Royal Sussex County Hospital-Brighton-United Kingdom-C United Kingdom Brighton Brighton
254 Bristol Haematology and Oncology Centre-Bristol-United Kingdom-C United Kingdom Gloucestershire Bristol
255 Christie Hospital NHS Foundation Trust-Manchester-United Kingdom-C United Kingdom Manchester Manchester
256 Royal Cornwall Hospital-Truro-United Kingdom-C United Kingdom Cornwall Cornwall
257 Royal Preston Hospital-Preston-United Kingdom-C United Kingdom Lancashire Preston
258 The Royal Wolverhampton Hospitals NHS Trust-Wolverhampton-United Kingdom-C United Kingdom Wolverhampton Wolverhampton
259 Royal Surrey County Hospital NHS Foundation Trust-Guidlford, Surrey-United Kingdom-C United Kingdom Surrey Guildford
260 Guy's & St THomas' NHS Foundation Trust-London-United Kingdom-C United Kingdom London London
261 Singleton hospital-Swansea-United Kingdom-C United Kingdom West Glamorgan Swansea
262 Tennessee Oncology PLLC-Chattanooga-United States-C United States Tennessee Chattanooga
263 Duke University Medical Center-Durham-United States-C United States North Carolina Durham
264 Mayo Clinic Cancer Center-Rochester-United States-C United States Minnesota Rochester
265 Tyler Cancer Center-Tyler-United States-C United States Texas Tyler
266 Northeast Georgia Cancer Care, LLC-Athens-United States-C United States Georgia Athens
267 Ohio Sate University-Columbus-United States-C United States Ohio Columbus
268 Kaiser Permanente Medical Center-San Jose-United States-C United States California San Jose
269 Kaiser Permanente Medical Center-San Francisco-United States-C United States California San Francisco
270 H. Lee Moffitt Cancer Center & Research Institute-Tampa-United States-C United States Florida Tampa
271 University of Chicago Medical Center-Chicago-United States-C United States Illinois Chicago
272 University Maryland Hospital-Baltimore-United States-C United States Maryland Baltimore
273 University of California and Medical Center-San Diego-United States-C United States California La Jolla
274 The University of Minnesota-Minneapolis-United States-C United States Minnesota Minneapolis
275 Loyola University Medical Center 1-Maywood-United States-C United States Illinois Maywood
276 Medical University of South Carolina-Charleston-United States-C United States South Carolina Charleston
277 Fox Chase Cancer Center-Philadelphia-United States-C United States Pennsylvania Philadelphia
278 Fox Chase Cancer Center-Philadelphia-United States-C United States Pennsylvania Philadelphia
279 LAC & USC Medical Center 3-Los Angeles-United States-C United States California Los Angeles
280 Rosewell Park Cancer Institute-Buffalo-United States-C United States New York Buffalo
281 Sammons Cancer Center-Dallas-United States-C United States Texas Dallas
282 Willamette Valley Cancer Center-Eugene-United States-C United States Oregon Springfield
283 Huntsman Cancer Institute- University of Utah-Salt Lake City-United States-C United States Utah Salt Lake City
284 MD Anderson Cancer Center-Orlando-United States-C United States Florida Orlando
285 The Emory Clinic-Atlanta-United States-C United States Georgia Atlanta
286 Eastern CT Hematology Oncology Associates-Norwich-United States-C United States Vermont Norwich
287 Cancer Care Centers of South Texas-San Antonio-United States-C United States Texas San Antonio
288 San Francisco Oncology Associates 1-San Francisco-United States-C United States California San Francisco
289 Southeast Nebraska Cancer Center-Lincoln-United States-C United States Nebraska Lincoln
290 Kaiser Permanente, Oakland-Oakland-United States-C United States California Oakland
291 Illinois Cancer Care-Peoria-United States-C United States Illinois Peoria
292 Karmanos Cancer Institute-Detroit-United States-C United States Michigan Detroit
293 Northwestern University-Chicago-United States-C United States Illinois Chicago
294 Rhode Island Hospital-Providence-United States-C United States Rhode Island Providence
295 The Miriam Hospital-Providence-United States-C United States Rhode Island Providence
296 University of Pennsylvania-Philadelphia-United States-C United States Pennsylvania Philadelphia
297 Mayo Clinic of Scottsdale-Scottsdale-United States-C United States Arizona Scottsdale
298 Greater Baltimore Medical Center-Baltimore-United States-C United States Maryland Baltimore
299 Dartmouth-Hitchcock Medical Center-Lebanon-United States-C United States New Hampshire Lebanon
300 Northwestern Carolina Oncology and Hematology-Hickory-United States-C United States North Carolina Hickory
301 Cornell (New York Presbyterian Hospital)-New York-United States-C United States New York New York
302 Rush University Medical Center-Chicago-United States-C United States Illinois Chicago
303 The University of Texas Health Science Center-San Antonio-United States-C United States Texas San Antonio
304 North Mississippi Hematology & Oncology Assoc-Tupelo-United States-C United States Mississippi Tupelo
305 Case Western Reserve University-Cleveland-United States-C United States Ohio Cleveland
306 Duke University Medical Center-Durham-United States-C United States North Carolina Durhman
307 Seattle Cancer Care Alliance-Seattle-United States-C United States Washington Seattle
308 University of Virginia Health Systems-Charlottesville-United States-C United States Virginia Charlottesville
309 University of Cincinnati 3-Cincinnati-United States-C United States Ohio Cincinnati
310 Virginia Mason Medical Center 1-Seattle-United States-C United States Washington Seattle
311 University of California Irvine Medical Centre 3-Orange-United States-C United States California Orange
312 Meharry Medical College-Nashville-United States-C United States Tennessee Nashville
313 Texas Oncology, PA-Bedford-Bedford-United States-C United States Texas Bedford
314 UCSF Comprehensive Cancer Center-San Francisco-United States-C United States California San Francisco
315 Washington University, Barnes-Jewish Hospital-St. Louis-United States-C United States Missouri St. Louis
316 Utah Cancer Specialists-Salt Lake City-United States-C United States Utah Salt Lake City
317 University of Iowa-Iowa City-United States-C United States Iowa Iowa City
318 Beth Israel Deaconess Medical Cnt/Harvard Medical-Boston-United States-C United States Massachusetts Boston
319 Hudson Valley Urology-Poughkeepsie-United States-C United States New York Poughkeepsie
320 Hackensack University Medical Center-Hackensack-United States-C United States New Jersey Hackensack
321 University Of Texas MD Anderson Cancer Center 3-Houston-United States-C United States Texas Houston
322 Cedar Sinai Medical Center-West Hollywood-United States-C United States California Los Angeles
323 The West Clinic-Memphis-United States-C United States Tennessee Memphis
324 Kaiser Permanente Medical Center-Santa Clara-United States-C United States California Santa Clara
325 Highline Medical Oncology-Burien-United States-C United States Washington Burien
326 Tower Hematology Oncology Medical Group-Beverly Hills-United States-C United States California Beverly Hills
327 Doctors Medical Center -JC Robinson Reg Cancer Ctr-San Pablo-United States-C United States California San Pablo
328 Peachtree-Hematology Oncology Consultants-Atlanta-United States-C United States Georgia Atlanta
329 Urology of Virginia-Virginia Beach-United States-C United States Virginia Norfolk
330 Stanford University Clinical Cancer Center-Stanford-United States-C United States California Stanford
331 UMass Memorial Medical Center-Worcester-United States-C United States Massachusetts Worcester
332 Norris Comprehensive Cancer Center-Los Angeles-United States-C United States California Los Angeles
333 Temple University-Philadelphia-United States-C United States Pennsylvania Philadelphia
334 Indiana University Cancer Center-6-Indianapolis-United States-C United States Indiana Indianapolis
335 Virginia Oncology Associates-Hampton-United States-C United States Virginia Hampton
336 Lakeland Regional Cancer Center-Lakeland-United States-C United States Florida Lakeland
337 Columbia Presbyterian Medical Center-New York-United States-C United States New York New York
338 Kaiser Permanente Medical Center-Vallejo-United States-C United States California Vallejo
339 Joe Arrington Cancer Center-Lubbock-United States-C United States Texas Lubbock
340 Kaiser Permanente Walnut Creek-Walnut Creek-United States-C United States California Walnut Creek
341 Massachusetts General Hospital Cancer Center-Boston-United States-C United States Massachusetts Boston
342 The Vanderbilt Clinic-Nashville-United States-C United States Tennessee Nashville
343 Georgetown University Medical Center-Washington-United States-C United States District of Columbia Washington
344 Akron General Medical Center-Akron-United States-C United States Ohio Akron
345 Brinz Burroff Gurtler Russo Mds-Metairie-United States-C United States Louisiana Metairie
346 Jefferson Hospital-Philadelphia-United States-C United States Pennsylvania Philadelphia
347 Pennsylvania Oncology Hematology Associates-Philadelphia-United States-C United States Tennessee Memphis
348 Virginia Cancer Care-Richmond-United States-C United States Virginia Richmond
349 Cleveland Clinic-Cleveland-United States-C United States Ohio Cleveland
350 Hematology Oncology Medical Group of Fresno-Fresno-United States-C United States California Fresno
351 Kaiser Permanente - Roseville-Roseville-United States-C United States California Roseville
352 Medical Oncology Associates-Spokane-United States-C United States Washington Spokane
353 St. Louis VA Medical Center-St. Louis-United States-C United States Missouri St. Louis
354 Front Range Cancer Specialists-Fort Collins-United States-C United States Colorado Fort Collins
355 New York Oncology Hematology-Albany-United States-C United States New York Albany
356 Providence Medical Center-Portland-United States-C United States Oregon Portland
357 Beth Israel Comprehensive Cancer Center-New York-United States-C United States New York New York
358 Mercy Physicians of Oklahoma - Mercy Health Center-Oklahoma City-United States-C United States Oklahoma Oklahoma City
359 Florida Cancer-Ft. Myers-United States-C United States Virginia Ft. Myer
360 Feinberg School of Medicine Dept. of Urology-Chicago-United States-C United States Illinois Chicago
361 Suniti Medical Corporation-Merrillville-United States-C United States Indiana Merriville
362 Summit Cancer Ctr-2-Savannah-United States-C United States Georgia Savannah
363 Texas Oncology-Houston-United States-C United States Texas The Woodlands
364 Dana Farber Cancer Institute-Boston, MA-United States-C United States Massachusetts Boston
365 Comprehensive Cancer Centers of Nevada-Eastern-Las Vegas-United States-C United States Nevada Las Vegas
366 Florida Cancer Specialists-Fort Myers-United States-C United States Florida Fort Myers
367 Tennessee Oncology-Nashville-United States-C United States Tennessee Nashville
368 Oncology Hematology Care-Cincinnati-United States-C United States Ohio Cincinnati
369 University of Cincinnati-Cincinnati-United States-C United States Ohio Cincinnati
370 Duluth Clinic-Duluth-United States-C United States Minnesota Duluth
371 Lahey Clinic-Burlington-United States-C United States Massachusetts Burlington
372 Robert Wood Johnson Medical School-New Brunswick-United States-C United States New Jersey New Brunswick
373 Nebraska Medical Center-Omaha-United States-C United States Nebraska Omaha
374 David Geffen School of Medicine at UCLA-Los Angeles-United States-C United States California Los Angeles
375 Kaiser Satellite South San Francisco-South San Francisco-United States-C United States California South San Francisco
376 Clopton Clinic-Jonesboro-United States-C United States Tennessee Memphis
377 Methodist Eastbrook Cancer Center-Omaha-United States-C United States Nebraska Omaha
378 Park Nicollet Institute-St. Louis Park-United States-C United States Minnesota St. Louis Park
379 University of Miami - Sylvester Cancer Center-Miami-United States-C United States Florida Miami
380 Central Georgia Cancer Care, P.C.-Macon-United States-C United States Tennessee Memphis
381 Clinical Trials Research Associated, Inc.-Montebello-United States-C United States California Montebello
382 Kaiser Permanente Hayward-Hayward-United States-C United States California Hayward
383 Kaiser Permanente Sacramento-Sacramento-United States-C United States California Sacramento
384 St. Luke's - Roosevelt Hospital Center-New York-United States-C United States New York New York
385 University of Michigan-Ann Arbor-United States-C United States Michigan Ann Arbor
386 Johns Hopkins University-Baltimore-United States-C United States Maryland Baltimore
387 北京301 医院 中国 北京 北京
 

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